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Search: Posts Made By: myoak
Forum: General 07-05-2015, 08:31 AM
Replies: 6
Views: 2,941
Posted By myoak
May be off the sleep topic slightly Having been...

May be off the sleep topic slightly

Having been involved with MS issues for the last 33 years I’ve seen plenty of controversy surrounding various treatments. One called hyperbolic oxygen therapy...
Forum: General 07-03-2015, 07:29 AM
Replies: 16
Views: 6,284
Posted By myoak
Sue, thank you for the link you provided to the...

Sue, thank you for the link you provided to the pdf on the Rituxan treatment protocol. I had not seen that before. I do the same as you… gather and save information to keep abreast of treatment...
Forum: General 06-30-2015, 04:38 PM
Replies: 5
Views: 2,000
Posted By myoak
Sorry I have no experience or knowledge to offer...

Sorry I have no experience or knowledge to offer on the topic but wanted to acknowledge your post as interesting in hope that someone can respond better than I.
Forum: General 06-30-2015, 04:24 PM
Replies: 16
Views: 6,284
Posted By myoak
TY, Cvfactor for the great link, very...

TY, Cvfactor for the great link, very educational!

I need to correct my previous post, Roche is developing ocrelizumab, not Biogen. Today, Roche released this good news about ocrelizumab:...
Forum: General 06-27-2015, 07:52 PM
Replies: 7
Views: 5,079
Posted By myoak
More evidence that viruses contribute to MS and...

More evidence that viruses contribute to MS and add to the possibility that MS may be treated with an anti-viral drug as a DMT someday.

Remyelination impairment and HERV-W in Multiple...
Forum: General 06-25-2015, 10:24 AM
Replies: 16
Views: 6,284
Posted By myoak
Don't resign yourself to believing you cannot get...

Don't resign yourself to believing you cannot get this drug if needed, Sue. You were one of the specific people in mind when I thought about posting on rituximab.

There are a number of MSers on...
Forum: General 06-24-2015, 04:24 PM
Replies: 16
Views: 6,284
Posted By myoak
Aggressive or Progressive MS?

One treatment possibility is Rituximab

From the first study below it appears rituximab can be effective against aggressive MS.

Rituximab appears in the second study to be a superior drug to some...
Forum: General 06-24-2015, 08:38 AM
Replies: 60
Views: 16,654
Posted By myoak
Just to add a couple items about minocycline…...

Just to add a couple items about minocycline… there is an active Phase 3 trial which is nearing completion; hopefully, it will conclude and be written-up before the next ECTRIMS meeting later this...
Forum: General 06-21-2015, 12:43 PM
Replies: 5
Views: 3,236
Posted By myoak
Perhaps, your doctors believe MS might progress...

Perhaps, your doctors believe MS might progress faster w/o Tysabri. Unfortunately, there is only one way to know for sure but if you halt Tysabri and suffer permanent damage from MS progression there...
Forum: General 04-28-2015, 08:35 AM
Replies: 48
Views: 21,376
Posted By myoak
My bad if I contributed to “over-hyping” the...

My bad if I contributed to “over-hyping” the Biotin News. If there is one thing we all benefit from it is a critical look at presentations by drug companies. Often because of time constraints I post...
Forum: General 04-26-2015, 10:24 AM
Replies: 1
Views: 2,315
Posted By myoak
Increasing Tysabri Dosing Interval May Cut PML...

Increasing Tysabri Dosing Interval May Cut PML Risk

Medpagetoday posted the above titled article which may be Googled, part of which is quoted below:

“—No sacrifice of efficacy seen in...
Forum: General 04-25-2015, 08:12 AM
Replies: 48
Views: 21,376
Posted By myoak
MD1003 Biotin HIGHLIGHTS “First time a drug has...

MD1003 Biotin HIGHLIGHTS

“First time a drug has decreased the rate of disease progression in addition to improving a significant proportion of patients with progressive MS.

“ ….12.6% of patients in...
Forum: General 04-17-2015, 08:09 AM
Replies: 48
Views: 21,376
Posted By myoak
GREAT NEWS!!! HUGE SUCCESS!!! MedDay announces...

GREAT NEWS!!! HUGE SUCCESS!!!


MedDay announces its pivotal Phase III study of MD1003 in patients with Progressive Multiple Sclerosis meets primary endpoint

~ Detailed Phase III data will be...
Forum: General 04-13-2015, 10:28 AM
Replies: 5
Views: 4,090
Posted By myoak
Indirect comparisons involving NEDA (No Evidence...

Indirect comparisons involving NEDA (No Evidence of Disease Activity)

NEDA is currently defined as having no relapses, MRI lesions and disability progression.

If brain shrinkage is added to those...
Forum: General 04-10-2015, 04:38 PM
Replies: 0
Views: 2,239
Posted By myoak
2nd PML case with Tecfidera

The case was reported in the NEJM...

"PML in a Patient without Severe Lymphocytopenia Receiving Dimethyl Fumarate"
http://www.nejm.org/doi/full/10.1056/NEJMc1413724

Unfortunately and tragically...
Forum: General 04-10-2015, 08:38 AM
Replies: 1
Views: 2,356
Posted By myoak
One class of bladder control drugs is associated...

One class of bladder control drugs is associated with dementia.

Gray et al. Cumulative use of strong anticholinergics and incident dementia: a prospective cohort study. JAMA Intern Med. 2015 Mar...
Forum: General 04-10-2015, 07:09 AM
Replies: 22
Views: 8,584
Posted By myoak
Just wanted to post this for those...

Just wanted to post this for those interested...

High doses of biotin in chronic progressive multiple sclerosis: A pilot study
http://www.msard-journal.com/article/S2211-0348(15)00006-1/fulltext...
Forum: General 04-10-2015, 06:45 AM
Replies: 48
Views: 21,376
Posted By myoak
The Phase 3 trail involving 150 patients will be...

The Phase 3 trail involving 150 patients will be reported on at the AAN meeting Friday April 24.
The report MAY hold bombshell good news of progressive MSers improving on Biotin!

We will soon know.
Forum: General 04-09-2015, 06:42 AM
Replies: 1
Views: 2,315
Posted By myoak
Reducing PML risk on Tysabri

A study of extending time between doses of Tysabri is ongoing. Last September data presented at the ACTRIMS/ECTRIMS meeting in Boston showed there were no cases of PML among 684 JCV positive MSers...
Forum: General 04-03-2015, 06:34 AM
Replies: 7
Views: 5,079
Posted By myoak
Those who want to know more about the Charcot...

Those who want to know more about the Charcot Project may do so by viewing a fascinating introduction of it on YouTube at http://www.youtube.com/watch?v=GTD1Bp-LZk44
Forum: General 03-30-2015, 07:12 PM
Replies: 22
Views: 8,584
Posted By myoak
Mouse, Obviously, anyone considering any...

Mouse,
Obviously, anyone considering any supplement should invest enough time to discern whether the supplement is appropriate for self. I'm sure everyone already knows that; don't know why I feel...
Forum: General 03-30-2015, 02:27 PM
Replies: 22
Views: 8,584
Posted By myoak
Oleanolic Acid Controls Oxidative Stress to...

Oleanolic Acid Controls Oxidative Stress to Protect Against Optic Nerve Degeneration in an Experimental Model of Multiple...
Forum: General 03-28-2015, 07:09 AM
Replies: 22
Views: 8,584
Posted By myoak
Those who want to research could Google...

Those who want to research could Google "Oleanolic acid protects optic nerve"

Oleanolic and Oleanic are the same thing, different spelling.

Also, then Google "NU ZHEN ZI". It is a Chinese herb we...
Forum: General 03-25-2015, 10:21 AM
Replies: 7
Views: 5,079
Posted By myoak
The Missing Link between EBV and MS appears to be...

The Missing Link between EBV and MS appears to be that EBV activates HERV; HERV then provokes an immune response which becomes MS.

Activation of MSRV-Type Endogenous Retroviruses during Infectious...
Forum: General 03-19-2015, 10:00 AM
Replies: 60
Views: 16,654
Posted By myoak
Thanks for the articles and links. Albuterol...

Thanks for the articles and links. Albuterol appears to have good effect in MS and immune system diseases.
Showing results 1 to 25 of 28

 
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