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Old 06-26-2018, 01:32 PM
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Dave @ ActiveMSers
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Location: Albuquerque, NM
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Default STUDY: High intensity interval training for people with MS: A systematic review

Mult Scler Relat Disord. 2018 Jun 13;24:55-63. doi: 10.1016/j.msard.2018.06.005. [Epub ahead of print]

High intensity interval training for people with multiple sclerosis: A systematic review.

Campbell E1, Coulter EH2, Paul L3.


Aerobic high intensity interval training (HIIT) is safe in the general population and more efficient in improving fitness than continuous moderate intensity training. The body of literature examining HIIT in multiple sclerosis (MS) is expanding but to date a systematic review has not been conducted. The aim of this review was to investigate the efficacy and safety of HIIT in people with MS.

A systematic search was carried out in September 2017 in EMBASE, MEDline, PEDro, CENTRAL and Web of Science Core collections using appropriate keywords and MeSH descriptors. Reference lists of relevant articles were also searched. Articles were eligible for inclusion if they were published in English, used HIIT, and included participants with MS. Quality was assessed using the PEDro scale. The following data were extracted using a standardised form: study design and characteristics, outcome measures, significant results, drop-outs, and adverse events.

Seven studies (described by 11 articles) were identified: four randomised controlled trials, one randomised cross-over trial and two cohort studies. PEDro scores ranged from 3 to 8. Included participants (n = 249) were predominantly mildly disabled; one study included only people with progressive MS. Six studies used cycle ergometry and one used arm ergometry to deliver HIIT. One study reported six adverse events, four which could be attributed to the intervention. The other six reported that there were no adverse events. Six studies reported improvements in at least one outcome measure, however there were 60 different outcome measures in the seven studies. The most commonly measured domain was fitness, which improved in five of the six studies measuring aspects of fitness. The only trial not to report positive results included people with progressive and a more severe level of disability (Extended Disability Status Scale 6.0-8.0).

HIIT appears to be safe and effective in increasing fitness in people with MS and low levels of disability. Further research is required to explore the effectiveness of HIIT in people with progressive MS and in those with higher levels of disability.

Dave Bexfield
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Old 12-21-2018, 08:00 PM
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Dave @ ActiveMSers
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Barts of London also weighed in on this....

All baring one study revealed improvements in either peak VO2 or VO2 max in MS. There was also improvements in peak power after exercise or following a couple of sessions - this is felt to be due to positive outcome on muscle contractile characteristics. In terms of adverse events, only one study reported knee or leg pain whilst cycling, but overall it was felt to be safe and an effective way of improving fitness in MS.

So what's stopping you?
Dave Bexfield
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Old 12-29-2018, 10:23 AM
Spacecake Spacecake is offline
Junior Optimistic Misfit
Join Date: Nov 2018
Posts: 8
Default Gratitude from this cyclist!

You gave me BeYOUtiful advice during my second month post diagnosis...which I very much took to heart & I got off the scary internet & then got back on my bike.

There are so many overwhelming options out there of ‘this’ diet and ‘this’ exact exercise...and it’s crazy scary/a little ‘buy now now now’...

Your advice helped, I’m finding my exercise path & just came back to your site to say thank you for the help and humor you gave to me (& well everyone!)

Thank you also for posting about this study - very cool!! Ok off to
Stretch and then
Exercise with
(T) = yes doing that too!!!

Ciao & happy almost 2019!!
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exercise study

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