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Old 04-16-2018, 11:11 AM
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Dave @ ActiveMSers
Join Date: Jun 2008
Location: Albuquerque, NM
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Default Review of 21 MS wellness articles: what is best for progressive MS?

Current Treatment Options in Neurology

May 2018

Exploring Wellness Interventions in Progressive Multiple Sclerosis: an Evidence-Based Review

Authors: Myriam Venasse, Thomas Edwards, Lara A. Pilutti

First Online: 10 April 2018


Purpose of review
There has been recent interest in the role of lifestyle and wellness-based approaches in the treatment and management of multiple sclerosis (MS). These approaches may be particularly relevant for patients with progressive MS, considering limited therapeutic options currently available. The purpose of this review is to examine the role of wellness-based interventions including exercise training, emotional well-being therapies, and dietary modification in patients with progressive MS.

Recent findings
We conducted a literature search on the efficacy of wellness-based interventions in patients with progressive MS published between 1985 and July 2017. The level of evidence for each trial was evaluated using the American Academy of Neurology criteria. Overall, 21 articles reporting on 16 wellness-based interventions were identified: ten trials involved exercise training, three involved emotional wellness therapies, two involved dietary modification, and one was a combined wellness intervention.

There is level C evidence (possibly effective; one class II study) for the efficacy of aerobic exercise training on cardiorespiratory fitness in patients with progressive MS. There is level B evidence (probably effective; one class I study) for the efficacy of mindfulness training on psychological distress, depression, anxiety, pain, and quality of life in patients with progressive MS. There is inadequate evidence (level U) for efficacy of dietary modification (one class III study and one class IV study) and combined wellness interventions involving exercise training, meditation, and dietary modification (one class IV study). High-quality research is needed to provide evidence-based recommendations for wellness behaviors and lifestyle change in patients with progressive MS.

Dave Bexfield
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Old 04-16-2018, 01:28 PM
Hondo Hondo is offline
Optimistic Misfit
Join Date: Feb 2018
Posts: 11
Default What's the alternative? Duh

This is interesting from an academic perspective, but from a practical standpoint, how can you not do everything to maximize your best outcome?

1. Plant based diet ala Drs McDougall and Greger.
2. Rigorous exercise targeting cardio, strength, balance and flexibility.
3. Deep and broad social network to love people and yourself.
4. Make interesting goals and work towards them.
5. Don't smoke, take drugs or blow your money.
6. Know that one day science will have a cure and a fix and you'll be ready when that day comes.
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