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Old 04-17-2019, 04:52 PM
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Dave @ ActiveMSers
Join Date: Jun 2008
Location: Albuquerque, NM
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Default Leading MS researcher says HSCT should be first-line therapyŚwith a warning

Gavin Giovannoni is all in on HSCT... "if I had MS I would choose HSCT as my treatment." Nice to have researchers getting aboard this important treatment option. But he does have some caveats. -D

We have to be honest with our patients about the risks and the benefits of HSCT and why we will limit HSCT to those who will benefit the most. In fact, there is evidence that more advanced patients may actually be made worse by HSCT; the chemotherapy used to ablate the immune system is neurotoxic and may speed up the neuronal loss. In addition, infections are common when you have HSCT and infections are well known to worsen MS disability in more advanced disease.

Dave Bexfield
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