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Old 01-10-2018, 01:11 PM
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Default Exercise as a Countermeasure to Declining Central Nervous System Function in MS

The abstract does not have much beef, but the full article is available (link below) and it is an interesting read. "To our knowledge, the present article offers the first argument for exercise as a countermeasure for CNS decline in MS." - D

Exercise as a Countermeasure to Declining Central Nervous System Function in Multiple Sclerosis

Author
Robert W. Motl, PhD
Brian M. Sandroff, PhD

https://doi.org/10.1016/j.clinthera.2017.12.001

Abstract

Purpose
The decline of central nervous system (CNS) function is a hallmark characteristic of multiple sclerosis (MS) that can manifest as cognitive impairment. We believe that exercise represents a potential behavioral approach for counteracting the declines in CNS structure and associated function among persons with MS (ie, exercise as a countermeasure of CNS decline). This theory is important because disease-modifying drugs represent a first-line approach for modifying the immune system and its effects on the CNS, but these drugs do not generally demonstrate robust improvements in cognitive performance.

Methods
To the best of our knowledge, this article presents the first argument positioning exercise as a countermeasure for CNS decline in MS.

Finding
The reviewed research indicates a proliferating body of evidence describing physical fitness, physical activity, and exercise effects on cognitive performance and neuroimaging outcomes (ie, CNS functioning) in MS, with the consistent and strong association between cognitive performance and neuroimaging outcomes in this population as a backdrop.

Implications
We further present a framework and future research directions for better positioning exercise as a possible neuroprotective behavior against declining CNS function in MS.

FULL ARTICLE (FREE): https://www.sciencedirect.com/scienc...49291817311062

FREE PDF OF ARTICLE:
https://ac.els-cdn.com/S014929181731...67acb0d4e5e4c0

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