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Exercise as a Countermeasure to Declining Central Nervous System Function in MS

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  • Exercise as a Countermeasure to Declining Central Nervous System Function in MS

    The abstract does not have much beef, but the full article is available (link below) and it is an interesting read. "To our knowledge, the present article offers the first argument for exercise as a countermeasure for CNS decline in MS." - D

    Exercise as a Countermeasure to Declining Central Nervous System Function in Multiple Sclerosis

    Author
    Robert W. Motl, PhD
    Brian M. Sandroff, PhD

    https://doi.org/10.1016/j.clinthera.2017.12.001

    Abstract

    Purpose
    The decline of central nervous system (CNS) function is a hallmark characteristic of multiple sclerosis (MS) that can manifest as cognitive impairment. We believe that exercise represents a potential behavioral approach for counteracting the declines in CNS structure and associated function among persons with MS (ie, exercise as a countermeasure of CNS decline). This theory is important because disease-modifying drugs represent a first-line approach for modifying the immune system and its effects on the CNS, but these drugs do not generally demonstrate robust improvements in cognitive performance.

    Methods
    To the best of our knowledge, this article presents the first argument positioning exercise as a countermeasure for CNS decline in MS.

    Finding
    The reviewed research indicates a proliferating body of evidence describing physical fitness, physical activity, and exercise effects on cognitive performance and neuroimaging outcomes (ie, CNS functioning) in MS, with the consistent and strong association between cognitive performance and neuroimaging outcomes in this population as a backdrop.

    Implications
    We further present a framework and future research directions for better positioning exercise as a possible neuroprotective behavior against declining CNS function in MS.

    FULL ARTICLE (FREE): https://www.sciencedirect.com/scienc...49291817311062

    FREE PDF OF ARTICLE:
    https://ac.els-cdn.com/S014929181731...67acb0d4e5e4c0

    Dave Bexfield
    ActiveMSers
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