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Promising Results In First Blinded Study Of Venous Insufficiency Prevalence In MS

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  • Promising Results In First Blinded Study Of Venous Insufficiency Prevalence In MS

    Have you read about this,
    More than 55 percent of multiple sclerosis patients participating in the initial phase of the first randomized clinical study to determine if persons with MS exhibit narrowing of the extracranial veins, causing restriction of normal outflow of blood from the brain, were found to have the abnormality.

    The results were reported by neurology researchers at the University at Buffalo.

    When the 10.2 percent of subjects in which results were border line were excluded, the percentage of affected MS patients rose to 62.5 percent, preliminary results show, compared to 25.9 percent of healthy controls.

    These preliminary results are based on the first 500 participants in the Combined Transcranial and Extracranial Venous Doppler Evaluation (CTEVD) study, which began at UB in April 2009. Investigators are planning to examine 500 additional subjects, who will be assessed in the second phase of the study with more advanced diagnostic tools. Complete data on the first 500 will be presented at the American Academy of Neurology meeting in April.
    I read it from http://www.medicalnewstoday.com/articles/178902.php
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  • #2
    Unfortunately, I just heard this news from the Rocky Mountain MS Center. Cutting edge treatments sometimes cut, but research thankfully is continuing...

    "After one fatality and another close call, researchers at Stanford University have stopped all treatments for chronic cerebrospinal venous insufficiency (CCSVI). The halt was reported in February's edition of the journal Annals of Neurology.

    The death, which occurred in August 2009, was the result of a brain hemorrhage following a stenting procedure. Another patient underwent emergency open heart surgery in November 2009 after a dislodged jugular vein stent wound up in the right ventricle of the heart.

    As stated in the last edition of eMS News, studies on CCSVI and their suggested relevance to MS have, to date, been preliminary and need to be confirmed before patients undergo invasive procedures to correct what is currently only a hypothesized problem. With the halt of the Stanford University procedures, the University of Buffalo remains the only university that we are aware of that continues to look into CCSVI and MS. However, the National MS Society anticipates funding several additional research teams to investigate this topic, which will hopefully bring clarity to this question in the near future."

    More here:

    http://www.medicalnewstoday.com/articles/181717.php
    Dave Bexfield
    ActiveMSers

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