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American ginseng does not improve fatigue in multiple sclerosis: a single center randomized double-blind placebo-controlled crossover pilot study.
Kim E, Cameron M, Lovera J, Schaben L, Bourdette D, Whitham R.
Neurology Service &MS Center of Excellence-West, Portland VA Med. Center/Dept of Neurology, Oregon Hlth & Sci. Uni., Portland, OR, USA.
This study examined the safety and efficacy of an escalating dose (100 mg, 200 mg, 400 mg/day) of American ginseng over 6 weeks in a single-center, randomized, double-blind, placebo-controlled, crossover trial with 56 subjects with multiple sclerosis and fatigue. There were no serious adverse events but fatigue on ginseng, as assessed by the Fatigue Severity Scale, was not significantly different from fatigue on placebo.
Kim E, Cameron M, Lovera J, Schaben L, Bourdette D, Whitham R.
Neurology Service &MS Center of Excellence-West, Portland VA Med. Center/Dept of Neurology, Oregon Hlth & Sci. Uni., Portland, OR, USA.
This study examined the safety and efficacy of an escalating dose (100 mg, 200 mg, 400 mg/day) of American ginseng over 6 weeks in a single-center, randomized, double-blind, placebo-controlled, crossover trial with 56 subjects with multiple sclerosis and fatigue. There were no serious adverse events but fatigue on ginseng, as assessed by the Fatigue Severity Scale, was not significantly different from fatigue on placebo.