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-   -   STUDY: Endurance training is feasible in severely disabled patients w/progressive MS (http://forums.activemsers.org/showthread.php?t=1404)

ActiveMSers 09-26-2013 09:59 AM

STUDY: Endurance training is feasible in severely disabled patients w/progressive MS
 
Endurance training is feasible in severely disabled patients with progressive multiple sclerosis

AG Skjerbæk1
M Næsby1
K Lützen1
AB Møller2,6
E Jensen1
I Lamers5
E Stenager3,4
U Dalgas2

1The MS-Hospitals in Ry and Haslev, Denmark
2Department of Public Health, Section of Sport Science, Aarhus University, Denmark
3MS-clinic of Southern Jutland (Sønderborg, Vejle, Esbjerg), department of neurology, Sønderborg, Denmark
4Institute of Regional Health Services, University of Southern Denmark
5Biomedical Research Institute, University of Hasselt, Belgium
6Research Laboratory for Biochemical Pathology, Institute of Clinical Medicine, Aarhus University Hospital, Denmark

•Anders Skjerbæk, The MS-Hospital in Ry, Klostervej 136, 8680 Ry, Denmark.

Abstract

This study tested whether upper-body endurance training (ET) is feasible and can be performed at sufficient intensity to induce cardiovascular adaptations in severely disabled patients with progressive multiple sclerosis (MS). Eleven progressive MS patients (6.5 ≤ EDSS ≤ 8.0) scheduled for a four-week inpatient rehabilitation program were randomized to a control group (CON, n = 5) that received standard individualized MS rehabilitation or an intervention group (EXE, n = 6) that in addition received 10 sessions of predominantly upper-body ET. One patient dropped out of the EXE group (drop-out rate: 1/6~17%) and no adverse events were recorded. The EXE group completed on average 9.3±0.8 sessions (~96.0±5%). During the ET sessions an average heart rate of 93.9±9.3beats*min–1 were sustained corresponding to 91.6±6.8% of the maximal pre-intervention heart rate. In the EXE group a trend toward a time*group interaction was seen for VO2peak (p = 0.06). ET is feasible in severely disabled patients with progressive MS and it can probably be performed at sufficient intensity to induce cardiovascular adaptations.


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