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Old 10-27-2017, 01:37 PM
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Default STUDY: What is the best home-based walking exercise prescription for people with MS

What is the best home-based walking exercise prescription for people with multiple sclerosis? A randomized controlled clinical trial

ECTRIMS Online Library. Aghaei N. Oct 27, 2017; 199914

Abstract: P1894
Type: Poster
Abstract Category: Late breaking news

Background and goals: People with multiple sclerosis (pwMS) suffer different symptoms that ultimately affect their quality of life (QOL). Exercise has been found to be helpful in managing symptoms and improving the health and QOL for pwMS. However, not all of the pwMS attend exercise sessions, especially over the longer term, due to different barriers they may face. Home-based exercise programs seem promising to allow patients to improve their symptoms and so QOL. Walking is an easy and simple way to get more active and improve health. The objective of this study was to determine which home-based walking exercise prescription is work best for reduction of symptoms and improvement of QOL among pwMS?

Methods: This was a randomized controlled clinical trial. Participants (N=76, EDSS≤4) were randomized into one of the following groups:
(1) 6 minutes walk (6MW)-twice per day,
(2) 6MW-once per day,
(3) 30 minutes walk (30MW)- once per day,
(4) 30MW-3 times per week,
(5) 45 minutes walk-2 times per week, and
(6) control group.
Participants performed their prescription over a period of 3 months. The main outcomes were pain, fatigue, depression, anxiety, and QOL that were measured using 0-10 Numeric Rating Scale (NRS), the Modified Fatigue Impact Scale (MFIS), the Hospital Depression and Anxiety Scale (HADS), and RAND-36 Health Survey, respectively.

Results: 6MW- twice per day and 30MW- 3 times per week were the most effective walking prescription followed by 30MW- once per day and 6MW-once per day. Pain (p=0.02) and fatigue (p=0.0005) were highly affected with 6MW-twice per day, while depression (p=0.001) and anxiety (p=0.04) most decreased with 30MW-3 times per week. The highest improvement of QOL score was observed in first and second groups, respectively.

Conclusions: The results of this study confirm that pwMS can walk at an appropriate self-paced intensity and duration to achieve positive results for the reduction of their symptoms and improvement of their QOL; however, 6MW- twice per day and 30MW-3 times per week were the most effective walking prescriptions.
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