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Leading MS Researcher: Is HSCT a no brainer, even for first-line treatment?

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  • Leading MS Researcher: Is HSCT a no brainer, even for first-line treatment?

    Interesting take and one that deserves attention. -D

    I recently had a patient of mine who has been desperate to be treated with alemtuzumab actually ask if he can change his mind and rather be referred for AHSCT (autologous hematopoietic stem cell transplantation). Why? Because the chances of being put into long term remission, and hence potentially being cured of having MS, seems to be much higher with AHSCT. This particular patient has no concerns about the risks associated with alemtuzumab or AHSCT. The most important concern on his radar is his long term outcome. He wants a healthy brain when he gets older.

    This is why this most recent paper on the long term outcome of Italian patients who received AHSCT adds to the mounting evidence base of the effectiveness of AHSCT. In patients with relapsing-remitting treated with AHSCT, MS 86% and 71% were free of disability worsening at 5 and 10 years, respectively. These figures for patients with progressive MS were 71% and 57% at 5 and 10 years, respectively.

    https://multiple-sclerosis-research..../a-no-brainer/
    Dave Bexfield
    ActiveMSers
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