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The Pick: ECTRIMS Abstract P751: Sormani MP, Schiavetti I, Signori A, et al. Autologous hematopoietic stem cell transplantation in multiple sclerosis: A meta-analysis.
The Findings: In a pooled meta-analysis that included 15 clinical trials or series, about 67 percent of MS patients who underwent hematopoietic stem cell transplantation were estimated to have achieved a no-evidence-of-disease-activity state for at least five years.
Why It's Important: This meta-analysis of high-dose immunoablation and stem cell rescue studies showed benefit, especially in younger patients with active disease. And this will, hopefully, lead to an international controlled clinical trial comparing this approach to other highly effective therapies.
Read the Neurology Today article, "Meta-Analysis Shows Stem Cell Transplantation Halts MS Progression for At Least Five Years," at http://bit.ly/NT-stemcellMS.
The Pick: ECTRIMS Abstract P751: Sormani MP, Schiavetti I, Signori A, et al. Autologous hematopoietic stem cell transplantation in multiple sclerosis: A meta-analysis.
The Findings: In a pooled meta-analysis that included 15 clinical trials or series, about 67 percent of MS patients who underwent hematopoietic stem cell transplantation were estimated to have achieved a no-evidence-of-disease-activity state for at least five years.
Why It's Important: This meta-analysis of high-dose immunoablation and stem cell rescue studies showed benefit, especially in younger patients with active disease. And this will, hopefully, lead to an international controlled clinical trial comparing this approach to other highly effective therapies.
Read the Neurology Today article, "Meta-Analysis Shows Stem Cell Transplantation Halts MS Progression for At Least Five Years," at http://bit.ly/NT-stemcellMS.