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I've never had any immediate issues from any immunization, from the flu shot to tetanus. Well, this second round of shots, which was the same as round one, put the hurt on me. And not just in my arms. A listed side effect is flu-like symptoms and last night I could barely walk. My temp must have been around 100 degrees, which obviously still wallops me. Feeling pretty much normal today, but the arms are still painful. Meh, nothing a little single malt can't fix. 