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A controversial condition coined and championed by Italian doctor Paolo Zamboni as the key to treating multiple sclerosis doesn’t appear to exist, according to a new study published in a leading Canadian medical journal. But the veinoplasty procedure, used to treat the non-existent condition known as chronic cerebrospinal venous insufficiency, may yet help some people with MS.
The idea that CCSVI, which refers to blocked or abnormal neck veins, plays a pivotal role in MS has been a controversial, hotly debated topic for the last five years in Canada, which has one of the world’s highest rates of the disease. The theory was developed by Zamboni, an Italian vascular surgeon, and brought to public attention by media reports, including in The Globe and Mail. Thousands of Canadians have travelled overseas and payed $20,000 or more to have veinoplasty, a procedure to prop open the neck veins to promote blood flow.
The new study, published in the Canadian Medical Association Journal on Monday, examined 120 patients with MS and 60 healthy controls and found no meaningful difference in vein abnormalities between the groups. The authors, led by Dr. Fiona Costello at the University of Calgary, conclude that their findings “revealed significant methodologic concerns” about the proposed diagnostic criteria for CCSVI that “challenge their validity.”
It’s just the latest in a slew of scientific papers that have cast serious doubt on the existence of a condition that supposedly interferes with normal blood flow and leads to an accumulation of iron in the brain. Many studies have found that venous abnormalities are quite common in healthy people and that many who have MS don’t have venous malformations.
http://www.theglobeandmail.com/life/...ticle18948065/
(dailyRx News) While the exact cause of multiple sclerosis (MS) remains unclear, research over the years has pointed to some potential culprits. Now, it seems that one possible cause of MS could be ruled out.
A recent study found that chronic cerebrospinal venous insufficiency (CCSVI), first introduced as a possible factor contributing to MS in 2009, was not more common among patients with MS than people who were healthy.
http://www.dailyrx.com/chronic-cereb...r-its-symptoms
The idea that CCSVI, which refers to blocked or abnormal neck veins, plays a pivotal role in MS has been a controversial, hotly debated topic for the last five years in Canada, which has one of the world’s highest rates of the disease. The theory was developed by Zamboni, an Italian vascular surgeon, and brought to public attention by media reports, including in The Globe and Mail. Thousands of Canadians have travelled overseas and payed $20,000 or more to have veinoplasty, a procedure to prop open the neck veins to promote blood flow.
The new study, published in the Canadian Medical Association Journal on Monday, examined 120 patients with MS and 60 healthy controls and found no meaningful difference in vein abnormalities between the groups. The authors, led by Dr. Fiona Costello at the University of Calgary, conclude that their findings “revealed significant methodologic concerns” about the proposed diagnostic criteria for CCSVI that “challenge their validity.”
It’s just the latest in a slew of scientific papers that have cast serious doubt on the existence of a condition that supposedly interferes with normal blood flow and leads to an accumulation of iron in the brain. Many studies have found that venous abnormalities are quite common in healthy people and that many who have MS don’t have venous malformations.
http://www.theglobeandmail.com/life/...ticle18948065/
(dailyRx News) While the exact cause of multiple sclerosis (MS) remains unclear, research over the years has pointed to some potential culprits. Now, it seems that one possible cause of MS could be ruled out.
A recent study found that chronic cerebrospinal venous insufficiency (CCSVI), first introduced as a possible factor contributing to MS in 2009, was not more common among patients with MS than people who were healthy.
http://www.dailyrx.com/chronic-cereb...r-its-symptoms