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STUDY: Combination of Mediterranean diet and exercise reduces fatigue in MS

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  • STUDY: Combination of Mediterranean diet and exercise reduces fatigue in MS

    This is not surprising. It makes sense that a smart diet and exercise lowers fatigue, not just in MSers but likely in the general population as well. - D

    The effect of Mediterranean diet and exercise as a complementary therapy in fatigue of patients with relapsing remitting MS (RRMS)

    M. Abolhasani1, S. Razeghi Jahromi2, M.A. Sahraian1 1Tehran University of Medical Sciences, MS Research Center, Neuroscience Institute, 2Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran

    Background: Multiple sclerosis(MS) is an immune-mediated disease of the central nervous system that characterised by disabling symptoms of which excessive fatigue is the most frequent. Fatigue is reported as the most invalidating symptom in MS. Various mechanisms directly and indirectly related to the disease and physical inactivity have been reported to contribute to the fatigue. Exercise therapy and change in a regular diet can induce physiological and psychological effects that may counter these mechanisms and reduce fatigue in MS.

    Methods: 70RRMS patients (age:26-41 years) with Expanded Disability Status Scale (EDSS) less than 5.5 were enrolled .Control group (n= 35) received isocaloric Mediterranean diet and intervention group received isocaloric Mediterranean dietary plus an exercise program consist of a stretching exercise program every days and 3 days strengthening program for large muscle groups in upper and lower limbs. The patients visited every three months throughout the study. The usual dietary intake and physical activity was assessed using 3-day food recall and International Physical Activity Questionnaire (IPAQ) respectively. FSS(fatigue severity scale) was evaluated at the first and the end of 6 months after beginning of the study. The adherence to Mediterranean diet and exercise was assessed using Mediterranean dietary score based on FFQ and a log book respectively. The scores of two groups were then compared using statistical tests such as repeated measures ANOVA test.

    Results: The results indicated significant changes in the intervention group in comparison to the control group in FSS: -6.9, P-value = 0.02.

    Conclusion: Mediterranean diet plus exercise might have beneficial effects as a complementary therapy in reduction of fatigue in RRMS patients with EDSS< 5.5.
    Dave Bexfield